Pharmaceutical Contract Manufacturing for CIS Countries: A Growing Opportunity for Indian Pharma Business
Overview of Sitagliptin Tablets
Sitagliptin is a DPP-4 inhibitor that is used as a first-line or add-on oral treatment for type 2 diabetes, and India also has the world’s second-largest diabetic population — over 100 million individuals—with new cases emerging each year. These generic sitagliptin pills and FDCs (e.g., sitagliptin + metformin) are in high demand in hospitals, clinics, and retail pharmacies because of their low cost and increased awareness.
However, this increased demand of sitagliptin manufacturers in India, this is defined by the fact that many branded pharmaceutical companies outsource sitagliptin tablet manufacturing to low-cost third-party facilities rather than investing in their own API or formulation operations. Even doctors favor DPP-4 inhibitors, such as sitagliptin, since they have fewer adverse effects, are well tolerated, and can be used with other anti-diabetic medications.
Moreover, in India, leading third-party manufacturing companies like ASPO Pharma are so popular. They can produce sitagliptin tablets in various strengths (e.g., 25 mg, 50 mg, 100 mg) using WHO-GMP facilities. In this, there is also a huge role and impact of the regulatory licenses. Many Indian plants hold DCGI licenses and offer EU-GMP compliance for export. Along with the cost savings, it is defined that outsourcing can significantly reduce setup expenses for marketing organizations, and it can also give you quick market entry in various markets. Thus, you will have the facilities to deal with tested formulas, package designs, and quality control in place. Consequently, there is a huge business scope and demand for the sitagliptin tablets manufacturer and supplier in India.
Benefits of Sitagliptin Tablets
Sitagliptin is an oral prescription medication that falls under the category of DPP-4 inhibitors. It is primarily used to assist in managing type 2 diabetes mellitus. This includes:
Improves Blood Sugar Control
Sitagliptin reduces blood glucose levels by increasing insulin release following meals. This also reduces the quantity of sugar produced by the liver.
Weight Neutral
Unlike several diabetic medications, sitagliptin is generally weight neutral, which means it rarely causes weight gain, a significant benefit for diabetes treatment.
Low Risk of Hypoglycemia
When administered alone (or with metformin), it is less likely to cause low blood sugar than sulfonylureas.
Convenient Dosing
Typically administered once daily, with or without food, making it simple for patients to adhere to therapy
Can be combined with other Medicines
Works well in combination therapy (typically with metformin or sulfonylureas) for improved glucose control.
Improves HbA1c
Helps to reduce HbA1c (a critical indicator of long-term blood sugar control) by 0.5% to 0.8% on average
Well Tolerated
Sitagliptin is well tolerated by the majority of patients, with occasional moderate side effects such as headaches or upper respiratory infections.
Top Sitagliptin Brands in India
Januvia
Istavel
Zita
Sitaptin
Gliptin
Glyptend
Sitagliptin Combinations
Sitagliptin 50 mg + Metformin 500 mg
Sitagliptin 50 mg + Metformin 850 mg
Sitagliptin 50 mg + Metformin 1000 mg
What are the making skills of the leading Sitagliptin Tablets Manufacturer, ASPO Pharma?
Here’s a clear, practical description of the general stages required in making sitagliptin phosphate tablets under GMP conditions.
API Procurement and Testing:
Obtain sitagliptin phosphate monohydrate (active pharmaceutical ingredient) from a certified provider. After that, they perform quality control tests on identification, purity, assay, moisture content, and particle size.
Excipient Selection: As a leading sitagliptin tablets manufacturer in India, they ensure our sitagliptin tablets commonly contain the following excipients:
Diluent: microcrystalline cellulose, lactose
Binder: povidone (PVP K30).
Disintegrant: croscarmellose sodium
Lubricant: magnesium stearate
Glidant is colloidal silicon dioxide
Coating agents include hypromellose and titanium dioxide (for film coating)
Weighing & Dispensing:
Weigh the API and excipients accurately according to the batch manufacturing record (BMR). After this, we check the weights under controlled conditions.
Blend: In this API with diluents and binders in a high-shear mixer or blender to ensure uniform dispersion. Then we ensure to maintain the right mixing time and speed.
Granulation:
To produce granules, add granulating fluid (such as pure water or a binding solution). Moreover, we dry the grains to the desired moisture levels using a fluid bed dryer (FBD) or a tray dryer. Also, we try to utilize direct compression. If the API flow is good, this step may be avoided.
Milling and Sizing:
Now, their making team passes dried granules through a sieve or mill to produce a consistent particle size.
Final Blending:
This includes lubricants and glidants, and we also blend slowly to avoid excessive lubrication.
Why do you need to select Aspo Pharma’s sitagliptin phosphate manufacturing services in India?
If you come to one of the leading sitagliptin phosphate manufacturers in India, it will give them various benefits like cost-effective, risk-free expansion. This means our third-party manufacturing services allow you to add sitagliptin tablets to your product line without investing in costly facilities or research and development. With this, you merely pay for manufacturing; there is no need to manage machinery, labor, or API supply directly.
Moreover, we are known to always offer our manufacturing services with our WHO-GMP & DCGI-approved production facilities. This makes sure that our customers always get high-quality, safe, and effective tablets that fulfill domestic and export standards.
However, outsourcing our manufacturing services frees up your time and money to devote to branding, promotion, and market expansion. Thus, we additionally provide customized packaging and private labeling as well to help your business image.
On the other hand, scalability and flexibility are always attractive to our customers, which is a strong part of our services. This allows us to begin with small or moderate batch sizes and simply ramp up production as demand grows. We also benefit our customers with the flexible MOQ (minimum order quantities) that make it appropriate for both startups and established businesses.
Furthermore, as one of the experienced sitagliptin manufacturers in India, we aid our customers with DCGI permissions and product registration, stability studies, and documentation. Hence, this reduces your regulatory headaches. Besides all of that, if you are using our medicine-making services on a contract basis, you can purchase APIs and excipients in bulk, passing on the cost benefits to you. Thus, you can gain higher margins to compete in the saturated diabetic market.
Conclusion Time
To come to the final part, we tell you that Aspo Pharma can be your decent and trusted manufacturing partner for the sitagliptin tablets. Thus, if you are looking to invest in the genuine sitagliptin tablets manufacturer in India, join us now.
Contact ASPO Pharma
Plant Address: Plot No – 10, Himuda Industrial Area, Bhatauli Kalan, Baddi, Himachal Pradesh 173205
Email Address: aspopharma@gmail.com
Phone Number: +91-8950191795
Email Address: aspopharma@gmail.com
Phone Number: +91-8950191795
